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TREE IN BUD - HRCT

November 09, 2012

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TREE IN BUD - HRCT

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Pyruvate Kinase Activity Assay Kit

http://www.sapphire-usa.com/700760?gclid=CJuHn-23xLMCFQh66wodikYAOA Pyruvate Kinase Activity Assay Kit A fluorescence-based method for detecting PK activity in erythrocyte lysates, plasma, cell culture samples, and tissue homogenates Pyruvate kinase (PK) catalyzes the formation of pyruvate and ATP from phosphoenolpyruvate and ADP. Deficient expression of PK in erythrocytes is one common cause of hemolytic anemia, and because it is expressed in tumor cells, PK has been studied as a potential tumor target. Cayman's Pyruvate Kinase Activity Assay provides a fluorescence-based method for detecting PK activity in erythrocyte lysates, plasma, cell culture samples, and tissue homogenates. In this assay, PK catalyzes the transfer of a phosphate group from PEP to ADP, yielding one molecule of pyruvate and one molecule of ATP. Pyruvate oxidase then catalyzes the conversion of pyruvate to acetyl phosphate, hydrogen peroxide (H2O2), and carbon dioxide. H2O2, in the presence of horser...

The Power House

A power house is an installation where energy in the form of electrical power is generated for distribution. The cells in our body also have energy producing powerhouses. Each cell contains not just one but many of these powerhouse organelles. The number and size of these organelles varies from cell to cell depending on the cell's functions. For instance, muscle cells need a lot of energy, and have 1000s of them per cell.Whereas each skin cell has just a few 100 of them. These powerhouse organelles go by the name 'mitochondria' Energy is released by the cell's powerhouse-mitochondria in the form of ATP(adenosine triphosphate). This energy (ATP) is extracted through the metabolism of food by a process called cellular respiration. The process of cellular respiration consists of four distinct stages, namely (1)Glycolysis (2)Pyruvate oxidation (3)Citric acid cycle, and (4)Oxidative phosphorylation i.e., the electron transport chain Of these 4 stages, glycoly...

Comics in Medicine_The Orphan Annie

Note the vacant eyes A famous 1900's daily American comic strip , Little Orphan Annie illustrated its lead character as a girl with red hair, red dress, and vacant circles for eyes . Papillary Carcinoma of the thyroid gland(PCT) is characterised by 2 distinct features on light microscopy , namely Orphan Annie eye nuclei and Psammoma bodies . In PCT,the cells of the thyroid gland i.e., the thyrocytes are large and show an abnormal nucleus and cytoplasm with several mitoses. The thyrocytes have characteristic "Orphan Annie eye nuclei" as explained in the figure below. The hand drawn illustration of Orphan Annie-eye nuclei reveals large nuclei cleared out in the center with powdery chromatin marginated to the periphery along with few open- and close-faced nuclei. 1=Orphan Annie-eye nuclei, 2=open-faced nuclei, 3=closed-faced nuclei Reference Link These are so named because they have a “cleared-out” appearance, similar to Little Orphan An...

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TREE IN BUD - HRCT

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